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In this animation adapted from Garland Science Publishing, a detailed look at DNA reveals the structural features that make up the famed double-helix molecule. The animation shows how the ladder-shaped DNA is constructed from chemical building blocks, including phosphates, sugars, and bases, held together by different kinds of chemical bonds. The narration further explains how the overall structure determines the charge and stability of the molecule, and how structure predicts key cellular functions of replication and transcription.